Case in point is cyber-athlete and double-amputee Aimee Mullins. When Aimee is not tearing up the track with her carbon-fibre blades, she wears artificial legs that look and feel exactly like normal legs -- hair follicles and all. She even likes to paint her nails and wear high heels.
Here's a video of Aimee Mullins at TED 1998 talking about running as a disabled athlete (very inspiring and I highly recommend you watch this) and her assortment of artificial limbs. It's a poignant example of how technologies can help people achieve self-actualization.